Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues
Experimental protocol for Droplet Hi-CA brief description of the Droplet Hi-C experimental procedure is provided below.FixationCells were cross-linked in 1% formaldehyde, which was...
Can Lynx Be Saved in the Balkans?
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Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein
Ethical statementThe research presented here complies with all relevant ethical regulations. All experiments involving animals were reviewed and approved by the Animal Care...
Global profiling of protein complex dynamics with an experimental library of protein interaction markers
Cultivation of yeast cellsFLiP libraryA 50-ml preculture of Saccharomyces cerevisiae (strain BY4716) was grown in a 250-ml Erlenmeyer flask from a single colony...
Uma estratégia para carregar, reencaixar e ler sequências de proteínas através de um nanoporo
Compreender a diversidade proteómica a nível molecular é essencial para os avanços na biologia e na medicina, mas a sequenciação de proteínas na...
Vitória dupla de Niemann – Pick | Biotecnologia da Natureza
Em uma semana, a Food and Drug Administration dos EUA aprovou dois tratamentos para a doença de Niemann-Pick tipo C (NPC). Um agente,...